Research award winners

Hugo-Schottmüller Award 2017

2017_Weis

PD Dr. med. Sebastian Weis: Metabolic Adaptation Establishes Disease Tolerance to Sepsis . Cell. 2017 Jun 15;169(7):1263-1275

Hugo Schottmüller Award 2017

2017_Broadley

Dr. rer. nat. Steven Broadley: Dual Track Clearance of Circulating Bacteria Balances Rapid Restoration of Blood Sterility with Induction of Adaptive Immunity . Cell Host Microbe. 2016 Jul 13;20(1):36-48


Roger Bone Award 2017

2017_Scheer

Dr. med. Christian Scheer: Quality Improvement Initiative for Severe Sepsis and Septic Shock Reduces 90-Day Mortality: A 7.5-Year Observational Study . Crit Care Med. 2017 Feb;45(2):241-252


Hugo Schottmüller Award 2016

Vettorazzi_2016

Dr. Sabine Vettorazzi: Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1 . Nature Communications 2015 Jul 17;6:7796

Roger Bone Award 2016

Bloos_2016

SepNet Study Group: Effect of Sodium Selenite Administration and Procalcitonin-Guided Therapy on Mortality in Patients With Severe Sepsis or Septic Shock. A Randomized Clinical Trial . JAMA Int Med. 2016 Sep 1;176(9):1266-76


Hugo Schottmüller Award 2015

2015_Weber

Dr. med. Georg Weber, Dresden: Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis. Science, Vol. 347, Issue 6227

Hugo Schottmüller Award 2015 (2nd prize)

Dr. med. Miriam Kalbitz: Role of extracellular histones in the cardiomyopathy of sepsis. The FASEB Journal, 2015 May;29(5):2185-93



Hugo Schottmüller Award 2015 (2nd prize)

2011_Mirakaj

PD Dr. med. Valbona Mirakaj: Vagus nerve controls resolution and pro-resolving mediators of inflammation. Journal of Experimental Medicine, vol. 211, no. 6, 1037-1048



Hugo Schottmüller Award 2014

2014_David

PD Dr. med. Sascha David, Hannover: Lung-Targeted RNA Interference Against Angiopoietin-2 Ameliorates Multiple Organ Dysfunction and Death in Sepsis. Crit Care Med 2014 Oct;42(10):e654-62

Roger Bone Award 2014

2014_Schäfer

PD Dr. med. Simon Schäfer, Essen: Hydrocortisone Fails to Abolish NF-kB1 Protein Nuclear Translocation in Deletion Allele Carriers of the NFKB1 Promoter Polymorphism (-94ins/delATTG) and Is Associated with Increased 30-Day Mortality in Septic Shock. PLoS One 2014 18;9(8)



Hugo Schottmüller Award 2013

2013_Hötzenecker

Wolfram Hötzenecker, Zürich: ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression. Nature Medicine, Volume 18, Number 1, January 2012

Roger Bone Award 2013

2013_WeberCarstens

PD Dr. med. Steffen Weber-Carstens, Berlin: Critical Illness Myopathy and GLUT4 - Significance of Insulin and Muscle Contraction. American Journal of Respiratory and Critical Care Medicine, Vol. 187, 2013



Hugo Schottmüller Award 2012

2012_Rauch

cand. med. Philipp Rauch, München: Innate Response Activator B Cells Protect Against Microbial Sepsis . Science 3 February 2012:
Vol. 335 no. 6068 pp. 597-601.

Roger Bone Award 2012

2012_Kolditz

Dr. med. Martin Kolditz, Dresden: Serum cortisol predicts death and critical disease independently of CRB-65 score in community-acquired pneumonia: a prospective observational cohort study . BMC Infectious Diseases 2012, 12:90.



B.Braun Critical Care Award 2012

2012_Schwab

Dr. rer. medic. Frank Schwab, Berlin: Understaffing, overcrowding, inappropriate nurse:ventilated patient ratio and nosocomial infections: which parameter is the best reflection of deficits? Journal of Hospital Infection Vol. 80, Issue 2, Pages 133-139.



Roger Bone Award 2011

2011_Adamzik

PD Dr. med. Michael Adamzik, Essen: Comparison of thromboelastometry with procalcitonin, interleukin 6, and C-reactive protein as diagnostic tests for severe sepsis in critically ill adults. Critical Care 2010, 14(5):R178

B.Braun Critical Care Award 2011

2011_Sasse

Dr. med. Michael Sasse, Hannover: Das pädiatrische Intensiv-Sepsisnetzwerk Norddeutschland.



Hugo Schottmüller Award 2011

2011_Mirakaj

Dr. med. Valbona Mirakaj, Frankfurt/Main: Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates inflammation. Proceedings of the National Academy of Sciences of the United States of America (PNAS), April 19, 2011, vol. 108, no. 16,6555–6560



Roger Bone Award 2010

2010_Schefold

Dr. Jörg C. Schefold, Berlin: Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial. American Journal of Respiratory an Critical Care Medicine

Roger Bone Award 2010

2010_Meisel

Dr. Christian Meisel, Berlin: Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial. American Journal of Respiratory and Critical Care Medicine



B.Braun Critical Care Award 2010

2010_Kola

PD Dr. med. Axel Kola, Berlin: Is there an association between nosocomial infection rates and bacterial cross transmissions?, Crit Care Med 2010 Vol. 38, No. 1

Hugo Schottmüller Award 2010

2010_SHerzig

Dr. Stephan Herzig, Heidelberg: In vivo PEPCK promoter mapping identifies disrupted hormonal synergism as a target of inflammation during sepsis in mice. Hepatology



Hugo Schottmüller Award 2009

2009_Rosenberger

PD Dr. med. P. Rosenberger, Tübingen: Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia. Nature Immunology

B.Braun Critical Care Award 2009

2009_Chaberny

PD Dr. med. I. F. Chaberny, Hannover
Surveillance with successful reduction of central line-associated bloodstream infections among neutropenic patients with hematologic or oncologic malignancies. Annals of Hematology



Hugo Schottmüller Award 2008

2008_Vogl

PD Dr. T. Vogl, Münster: MRP8 and MRP14 are novel endogenous activators of toll-like receptor 4 promotinglethal endotoxin-induced shock, Nature Medicine 13: 1042-1049

Roger Bone Award 2008

2008_Rafat

N. Rafat, Mannheim: Increased circulation endothelial progenitor cells in septic patients: Correlation with survival, Critical Care Medicine 2007; 35:1677-1684



B.Braun Critical Care Award 2008

2008_Nachtigall

Dr. I. Nachtigall, Berlin: Impact of Adherence to Standard Operating Pocedures for Pneumonia on Outcome of ICU Patients



Hugo Schottmüller Award 2007

2007_Wirtz

Dr. S. Wirtz, Mainz:
Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27, The Journal of Experimental
Medicine, 2006; 203: 1875-1881

Roger Bone Award 2007

2007_Schefold

Dr. med. J. C. Schefold, Berlin: A novel selevtive extracorporeal intervention in sepsis: immunoadsorption of endotoxin, interleukin-6, and complement-activating product 5a, Shock 2007



B.Braun Critical Care Award 2007

2007_Buerle

Dr. M. C. Bürle, Ludwigsburg: Regionales Netzwerk zur Umsetzung und Optimierung evidenz-basierter Therapien in der klinischen Intensivmedizin



Hugo Schottmüller Award 2006

2006_Schaefer

Prof. L. Schaefer, Frankfurt: The Matrix component biglycan is proinflammatory and signals through Toll-like receptor-4 and -2 in magrophages. The Journal of Clinical Investication 2005, Vol. 115, No. 8: 2223-2233.

Roger Bone Award 2006

2006_Westphal

PD Dr. med. M. Westphal, Münster: Effects of levosimendan on right ventricular afterload in patients with acute respiratory distress syndrome: A pilot study. Critical Care Medicine 2006, Vol. 34, No. 9: 2287-2293.



B.Braun Critical Care Award 2006

2006_Rinderknecht

Dr. med. F. Rinderknecht, Göppingen: Standard Operating Procedures (SOPs) - Mittel zur Einführung und Implementierung evidenzbasierter Therapiestrategien in der Intensivmedizin.

Research scholarship 2006

2006_Friedrich

PD Dr. med. Dr. rer. Nat Dipl. Phys. O. Friedrich, Heidelberg: Pathogenese der Myopathie bei Intensivpatienten.



Hugo Schottmüller Award 2005

2005_Knuefermann

Dr. P. Knüfermann, Bonn: Toll-like Receptor 2 Mediates Staphylococcus aureus-Induced Myocardial Dysfunction and Cytokine Production in the Heart. Circulation, 2005; 110:3693-3698

Roger Bone Award 2005

2005_Brueckmann

Dr. M. Brückmann; Mannheim: Prognostic value of plasma N-terminal pro brain natriuretic peptide in patients with severe sepsis. Circulation, 2005;112: 527-534



B. Braun Critical Care Award

2005_Kortgen

Dr. A. Kortgen, Homburg/Saar: Implementation of an evidence-based "standard operating procedure" and outcome. Critical Care Medicine, 2006; 34:943

Research scholarship 2005

2005_Glatzle

Dr. med. J. Glatzle, Tübingen: Protektive Effekte einer enteralen Immunonutrition auf die Entstehung von septischen Lungenfunktionsstörungen



Hugo Schottmüller Award 2004

2004_Merx

Dr. med. W. Merx, Aachen: HMG-CoA Reductase Inhibitor Simvastatin Profoundly Improves Survival in a Murine Model of Sepsis. Circulation 2004;109:2560-2565.

Roger Bone Award 2004

2004_Mayer

Dr. med. K. Mayer, Gießen: Parenteral Nutrition with Fish Oil Modulates Cytokine Response in Patients with Sepsis. Am J Respir Crit Care Med 2003;167:1321-1328.



Research scholarship 2004

2004_Gille

Dr. med. Ch. Gille, Tübingen: Etablierung eines Assays zur Quantifizierung der bakteriellen Phagoyztosekapazität von Makrophagen bei neonataler Sepsis.



Hugo Schottmüller Award 2003

2003_Hennecke

Dr. med. Ph. Henneke: Cellular Activation, Phagocytosis, and Bactericidal Activity Against Group B Streptococcus Involve Parallel Myeloid Differentiation Factor 88-Dependent and Independent Signaling Pathways. J Immunol 2002; 169:3970-3977

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2003_Riedemann

Dr. med. N. C. Riedemann: Regulation by C5a of Neutrophil Activation during Sepsis. Immunity 2003; 19:193-202


Roger Bone Award 2003

2003_Keh

Dr. med. D. Keh: Immunologic and Hemodynamic Effects of "Low-dose" Hydrocortisone in Septic Shock: a Double-Blind, Randomized, Placebo-controlled, Crossover Study. Am J Respir Crit Care Med 2003;167(4):512-20



Hugo Schottmüller Award 2002

2002_Senftleben

Dr. med. Uwe Senftleben: Habilitationsschrift "Funktion des IKK/NF-kB Signaltransduktionsweges bei der Lymphopoese" u.a. erschienen in: Science, Vol. 293 (24 August 2001)


Roger Bone Award 2002

2002_Huber-Lang

Dr. med. M. Huber-Lang: Protective effects of anti-C5a peptide antibodies in experimental sepsis. FASEB J, 15 (2001)

&

2002_Zweigner

Dr. med. J. Zweigner: High concentrations of lipopolysaccharide-binding protein (LBP) in serum of patients with severe sepsis or septic shock inhibit the lipopolysaccharide response in human monocytes. Blood, 89 (2001)